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. 2021 Apr 15;11:628624. doi: 10.3389/fonc.2021.628624

Figure 3.

Figure 3

The assuming targets miR-326-3p and miR-330-5p promoted aerpbic glycolysis in MKN45 and SGC7901 cells. (A, B). Relative expressions of miR-326-3p and miR-330-5p in GT, HDAC, PDAC. (C, D) Corelationship of circATP2B1 with miR-326-3p and miR-330-5p in GT, HDAC, PDAC. (E, F). Relative expressions of miR-326-3p and miR-330-5p in MKN45 and SGC7901 cells. (G, H). CCK8 assays were performed to evaluate cell viability in MKN45 and SGC7901 cells overexpressing or silence of miR-326-3p or miR-330-5p. (I) The glucose uptake assay (J) lactate accumulation, (K) ATP/ADP ratio. (L) NAD+/NADH ratio of MKN45 and SGC7901 cell lines stably overexpressing or silence of miR-326-3p (Data represented means±SD, n=3, *P<0.05, **P < 0.01 compared with miR-330-5p(+)NC group; # P < 0.05, ## P < 0.01 compared with miR-330-5p(-)NC group). (M) The glucose uptake assay (N) lactate accumulation, (O) ATP/ADP ratio. (P) NAD+/NADH ratio of MKN45 and SGC7901 cell lines stably overexpressing or silence of miR-330-5p. (Data represented means±SD, n=3, *P<0.05, **P < 0.01 compared with miR-330-5p(+)NC group; # P < 0.05, ## P < 0.01 compared with miR-330-5p(-)NC group).