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. 2021 Apr 30;11:652033. doi: 10.3389/fonc.2021.652033

Figure 4.

Figure 4

Phytochemicals inhibit bladder cancer cells proliferation by blocking cell cycle via suppressing various cyclins and CDKs, as well as upregulation of p21waf1 and p16-Ink4a in bladder cancer cells. The red ovals represent upregulated molecules by phytochemicals, and the blue ovals represent downregulated molecules by phytochemicals.