Table 4.
Percentage change of inflammatory marker concentration per 1 standard deviation increase in rest–activity parameters
| IgA (n = 121) | CRP (n = 118) | IL8 (n = 57) | IL1b (n = 60) | TNFα (n = 59) | MCP1 (n = 60) | |
|---|---|---|---|---|---|---|
| Mesor | –24 (–40.7, –2.7) | –4.5 (–31.9, 33.9) | 10.8 (–13.8, 42.5) | –10 (–36.6, 27.8) | 6.6 (–14.5, 32.8) | –31.5 (–44.6, –15.3) |
| p < 0.05 b, d | p = 0.79 | p = 0.42 | p = 0.55 | p = 0.56 | p < 0.01 a, c | |
| Acrophase | 7.6 (–15.9, 37.7) | –10 (–35, 24.8) | –6.1 (–28.1, 22.7) | –5.2 (–33.4, 35) | –3.5 (–23.4, 21.5) | –14.9 (–32.6, 7.5) |
| p = 0.56 | p = 0.52 | p = 0.64 | p = 0.76 | p = 0.76 | p = 0.17 | |
| Relative amplitude | 2.9 (–15.8, 25.6) | –32.6 (–47.8, –12.9) | 6.5 (–12.3, 29.4) | 16.1 (–11, 51.6) | –0.7 (–16.3, 17.7) | 3.2 (–13.8, 23.6) |
| p = 0.78 | p < 0.02 a, b, c, d | p = 0.52 | p = 0.26 | p = 0.93 | p = 0.73 | |
| Interdaily stability | 6.2 (–17.3, 36.6) | 0.2 (–28.4, 40.1) | 0.9 (–27.9, 41.3) | –11.9 (–44.5, 39.8) | –17.8 (–38.4, 9.7) | –33.3 (–50.1, –10.7) |
| p = 0.63 | p = 0.99 | p = 0.96 | p = 0.58 | p = 0.18 | p < 0.01 a, c | |
| Intradaily variability | –9.7 (–27.3, 12.2) | 19.7 (–10.7, 60.4) | –9.9 (–28.3, 13.3) | –6.6 (–32.2, 28.6) | –8.6 (–25.1, 11.6) | –22 (–36.4, –4.4) |
| p = 0.35 | p = 0.23 | p = 0.37 | p = 0.67 | p = 0.37 | p < 0.05 a, b, c, d | |
| M10 midpoint | –3.2 (–21.8, 19.7) | –16.1 (–36.6, 11.1) | 5.4 (–16.7, 33.5) | –13.8 (–37.1, 18.3) | 0.7 (–18, 23.7) | –8.3 (–25.9, 13.3) |
| p = 0.76 | p = 0.22 | p = 0.65 | p = 0.35 | p = 0.95 | p = 0.41 | |
| L5 midpoint | 10.1 (–11.7, 37.1) | 14.8 (–14.6, 54.3) | 30.8 (3.6, 65.2) | 43.4 (5.6, 94.9) | 11.5 (–9, 36.6) | 16.3 (–5.9, 43.7) |
| p = 0.39 | p = 0.36 | p < 0.05 a, b, c, d | p < 0.05 a, b, c, d | p = 0.29 | p = 0.16 | |
| CFI | 8.5 (–14.1, 37.1) | –23.7 (–44.1, 4.1) | 8.8 (–16.3, 41.5) | 8 (–24.7, 55) | –5.4 (–24.7, 19) | –5.9 (–26.1, 19.9) |
| p = 0.49 | p = 0.09 | p = 0.52 | p = 0.67 | p = 0.63 | p = 0.62 |
Data are expressed as mean (95 CI). Unit is %. (Model 1) the default model is adjusted for age, sex, grade, and school (school for IgA and CRP only). If significance was found in the default model, further adjustments were made as following: a(Model 2) Model 1 + total sleep duration. b(Model 3) Model 1 + daytime motor activity. c(Model 4) Model 2 + BMI z-score. d(Model 5) Model 3 + BMI z-score.
M10 midpoint, timing of most active 10-h episode; L5 midpoint, timing of the least active 5 h episode; CFI, circadian function index.