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. 2021 Mar 20;8(3):1933–1943. doi: 10.1002/ehf2.13219

Figure 2.

Figure 2

Finerenone treatment allowed improving ovariectomy‐induced reduction in glucose and insulin tolerance and reduction in myocardial ATP production. Assessments in control mice (CTL, black circles) and in mice after 4 months of ovariectomy (OVX, red squares) without or with 1 month finerenone treatment (OVX + Fine, green triangles). (A) Oral glucose tolerance test (OGTT) (n = 11, 9, 9). (B) Insulin tolerance test (ITT) (n = 13, 12, 9). (C) ATP production of subsarcolemmal mitochondria (n = 9, 9, 10). Data are mean ± standard error of the mean. Statistics: one‐way ANOVA plus Tukey, *P < 0.05 vs. CTL; † P < 0.05 vs. OVX.