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. 2021 Apr 8;8(3):1850–1860. doi: 10.1002/ehf2.13304

Table 2.

Correlation between plasma levels of evaluated miRNAs and degree of left ventricular inflammatory response, echocardiographic parameters of left ventricular function, and plasma concentration of markers of myocardial injury in patients with iCMP (n = 60)

r CD3+ CD68+ LVEF LVEDD LVESD Troponin T CK‐MB CRP ESR NT‐proBNP
miR‐21 0.26 0.45* −0.07 −0.02 −0.03 0.01 −0.10 0.50* 0.27 0.22
miR‐126 0.38 0.55* 0.06 −0.03 −0.03 −0.04 0.12 0.18 0.18 0.07
miR‐133a −0.21 −0.05 −0.13 −0.06 −0.09 0.03 0.04 0.30 0.29 0.18
miR‐146b −0.01 0.07 −0.11 0.12 0.16 −0.04 −0.07 0.31 0.37 0.22
miR‐155 −0.15 −0.22 −0.11 0.17 0.15 −0.05 0.03 0.01 −0.07 −0.05
miR‐206 −0.04 0.03 0.13 −0.14 −0.09 −0.06 0.33 0.03 −0.13 −0.06

CD3+, number of CD3‐positive T lymphocytes in left ventricular endomyocardial biopsy specimen; CD68+, number of CD68‐positive macrophages in left ventricular EMB specimen; CK‐MB, creatine kinase myocardial band; CRP, C‐reactive protein; ESR, erythrocyte sedimentation rate; iCMP, inflammatory cardiomyopathy; LVEDD, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end‐systolic diameter; miRNAs, microRNAs; NT‐proBNP, N‐terminal pro‐brain natriuretic peptide; r, Spearman correlation coefficient after Benjamini–Hochberg adjustment for multiple correlation testing.

*

Statistically significant correlation (P < 0.05).