Figure 2.

BBR alleviated lipid deposition in hepatocytes both in vivo and in vitro. (A-C) Lipid deposition of the mice was assessed by gross morphology (A), liver weight (B), HE staining and oil red staining (C) of liver tissue (n = 10). (D) Drug concentration screening of primary hepatocytes by cytotoxicity. (E-F) Oil red staining (E) and intracellular triglyceride content (F) of the primary hepatocytes incubated with blank, OA, OA+BBR, OA+ROT or OA+BBR+ROT for 24 h (n = 4). Data were expressed as means ± SEM. *P < 0.05.