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MiRNAs that regulate hepatocyte apoptosis in nonalcoholic fatty liver disease (NAFLD).
| MiRNA | Circulation level | Liver expression | Function* | Identified targets(references) |
|---|---|---|---|---|
| miR-223 | ↑88 | ↑89 | ↑? | IGF-1R81 |
| miR-24 | unknown | ↑90 | ↓? | BIM82 |
| miR-21 | ↑10,11 | ↑9,15 | ↓? | PDCD483 |
| miR-34a | ↑10,11 | ↑32,30 | ↑ | Sirt184-86 |
| miR-296 | unknown | ↓87 | ↓ | PUMA87 |
* ↑: promoting apoptosis; ↓: suppressing apoptosis.
