Table 6.

MiRNAs that regulate liver fibrosis in nonalcoholic fatty liver disease (NAFLD).

MiRNA	Circulation level	Liver expression	Function*	Identified targets(references)
miR-21	↑10,11	↑9,15	↑	SMAD7,111 PPARα16
miR-122	↑22,38	↓114	↓	HIF-1α, vimentin, MAP3K3114
miR-146a-5p	unknown	↓115	↓	Wnt1, Wnt5a115
miR-214	unknown	unknown	↑?	Sufu,118 Mig-6119
miR-130a-3p	unknown	↓120	↓	TGFBR1, TGFBR2120
miR-221-3p	unknown	↑121	↑?	GNAI2121
miR-223	↑88	↑89	↓	Nlrp3, Cxcl10, TAZ, Igf1r88
miR-29a	↓42	↓43	↓	CD3643