Table 2.
Imaging parameters for the three molecular subgroups; 1) IDH wildtype vs mutant, 2) IHD mutant/1p/19q codeleted vs IDH mutant/1p/19q intact, and 3) MGMT methylated vs MGMT unmethylated.
| IDH wildtype (n=11) Mean(range) | IDH mutant (n = 43) Mean(range) | p-value | Test Statistic | HDH-mt 1p/19q codeleted (n = 24) Mean(range) | IDH-mt 1p/19q intact (n = 19) Mean(range) | p-value | Test Statistic | MGMT methylated Mean( range) (n = 23) | MGMT unmethylated Mean(range) (n = 9) | p-value | Test Statistic | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | 57.09(27–71) | 43.23(23–71) | 0.006** | t=320 | 44.2(30–71) | 38.7(23–67) | 0.011* | t=2.81 | 48.6(32–65) | 48.6(23–67) | 0.44 | t=−0.83 |
| Sex | M, F = 3, 8 | M, F = 25, 18 | 0.181 | r = 3.14 | M, F = 13, 11 | M, F = 13, 6 | 0.34 | χ2 = 2.31 | M, F = 1, 8 | M, F = 13, 10 | 0.02* | χ2 = 7.39 |
| FLAIRVOL | 29052(1445–75116) | 34192(0–218140) | 0.63 | t=−0.47 | 20774(0–218140) | 27783(146–146030) | 0.45 | t=0.88 | 26997(1445–83239) | 33727(3461–218140) | 0.31 | t=−0.48 |
| CEVOL | 2203(0–7077) | 3090(0–27664) | 0.51 | t=−0.66 | 3420(0–27664) | 2171(0–24497) | 0.35 | t=−1.11 | 2212(0–7077) | 4033(0–27664) | 0.17 | t=−0.95 |
| CEVOL / FLAIRVOL | 0.17(0–1.15) | 0.14(0–1.82) | 0.79 | t=0.26 | 0.22(0–2.05) | 0.11(0–1.15) | 0.38 | t=0.98 | 0.19(0–1.15) | 0.12(0–052) | 0.31 | t=0.49 |
| Edge Contrast | 544.7(72–1561) | 1058.5(46–2741) | 0.008** | t=−2.97 | 632(46–2741) | 1369(72–1967) | 0.005** | t=−328 | 643(72–1368) | 1055(142–2741) | 0.03* | t=−1.88 |
| Homogeneity | 1.9(02–4.5) | 3.1(0.3–6.3) | 0.013* | t=−2.75 | 2.4(0.2–5.1) | 3.8(0.2–6.3) | 0.002** | t=−3.46 | 2.5(0.8–4.5) | 2.6(0.2–5.2) | 0.44 | t=−0.14 |
| Pixel Correlation | 6.8(0.9–11.3) | 11.8(2.2–33.3) | 0.001** | t=−3.65 | 12.3(2.2–28.5) | 13.2(0.9–33.3) | 0.17 | t=−1.26 | 8.1(4.8–14.8) | 9.8(0.9–18.3) | 0.10 | t=−1.26 |
**
p-value < 0.01
*
p-value < 0.05