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. Author manuscript; available in PMC: 2021 May 14.
Published in final edited form as: Ultrasound Med Biol. 2020 Feb 17;46(5):1224–1234. doi: 10.1016/j.ultrasmedbio.2020.01.008

Fig 1.

Fig 1.

Timeline of the study. Day 0 was defined as the day of pilocarpine administration and status epilepticus. Animals were allowed a 30-day period of post-status stabilization and seizure development. Behavioral seizures were monitored on Days 31 to 60, and Days 62 to 91. Magnetic Resonance Imaging (MRI), Quinolinic Acid injection (QA), and Focused Ultrasound + microbubbles (FUS) were performed at the indicated time points. Animals were euthanized on Day 92, and brains were prepared for histological assessment of sites of neuronal loss (Histo).