Table I.
Association between MTA1, SOX4 and EZH2 expression and clinicopathological parameters in esophageal squamous cell carcinoma.
| MTA1 | SOX4 | EZH2 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Item | Negative | Positive | P-value | Negative | Positive | P-value | Negative | Positive | P-value |
| Age (years) | 0.557 | 0.016 | 0.092 | ||||||
| <60 | 11 (4.8) | 71 (31.0) | 19 (8.3) | 63 (27.5) | 54 (23.6) | 28 (12.2) | |||
| ≥60 | 24 (10.5) | 123 (53.7) | 57 (24.9) | 90 (39.3) | 80 (34.9) | 67 (29.3) | |||
| Ethnicity | <0.001 | 0.035 | 0.130 | ||||||
| Han | 7 (3.1) | 112 (48.9) | 32 (14.0) | 87 (38.0) | 64 (27.9) | 55 (24.0) | |||
| Kazakh | 28 (12.2) | 82 (35.8) | 44 (19.2) | 66 (28.8) | 70 (30.6) | 40 (17.5) | |||
| Degree of differentiation | 0.395 | 0.725 | 0.003 | ||||||
| PD | 10 (4.4) | 36 (15.7) | 13 (5.7) | 33 (14.4) | 35 (15.3) | 11 (4.8) | |||
| MD | 17 (7.4) | 106 (46.3) | 42 (18.3) | 81 (35.4) | 73 (31.9) | 50 (21.8) | |||
| WD | 8 (3.5) | 52 (22.7) | 21 (9.2) | 39 (17.0) | 26 (11.4) | 34 (14.8) | |||
| Lymph node metastasis | 0.037 | 0.665 | 0.289 | ||||||
| No | 29 (12.7) | 126 (55.0) | 50 (21.8) | 105 (45.9) | 87 (38.0) | 68 (29.7) | |||
| Yes | 6 (2.6) | 68 (29.7) | 26 (11.4) | 48 (21.0) | 47 (20.5) | 27 (11.8) | |||
Values are expressed as n (%). MTA1, metastasis-associated protein 1; EZH2, enhancer of zeste homolog 2; PD, poorly differentiated; MD, moderately differentiated; WD, well differentiated.