Fig. 4.

In vivo experiment, four groups of mice were treated with PBS, laser, HPP, and HPP combined with laser, respectively. a Average body weight of tumor-bearing mice in each group during the treatment periods. b Relative tumor volumes (compared to the whole-body volume) of tumor-bearing mice in each group. c Representative photograph of excised tumors from euthanized mice. d Average tumor weight of treated mice in each group. e Representative photographs of tumor-bearing mice after different treatments (Scale bar = 200 μm). f H&E and g TUNEL staining imaging of the tumor sections after photothermal therapy (Scale bar is 100 μm). *p < 0.01 vs. other groups