Table 2.

Predicted consequential pairing of target region in the transcript and miR-424-5p

Target gene	Representative transcript	Gene name	Transcript position	Predicted consequential pairing of target region Transcript (top) and miRNA (bottom)	Site type
CCND1	ENST00000227507.2	Cyclin D1	1961–1967 3′UTR	(Transcript) 5′ CCAUUUUCUUAUUGCGCUGCUAC 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	7mer-A1
			2033–2040 3′UTR	(Transcript) 5′ CUCUUUCACAUUGUUUGCUGCUA 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	8mer
VEGFA	ENST00000372067.3	Vascular endothelial growth factor A	276–283 3′UTR	(Transcript) 5′CCAUUUUAUUUUUCUUGCUGCUA 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	8mer
CD40	ENSG00000101017	CD40, TNF receptor superfamily member 5	61–71 3′UTR	(Transcript) 5′ CUUCCUGGCUCCAACACUGCUGCUC 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	7mer
COX2	ENSG00000073756 (PTGS2)	Cyclooxygenase-2	165–179 3′UTR	(Transcript) 5′ UGAUUUGUUAUUAACAUUGAUCGCUG 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	6mer
INSR	ENSG00000171105	Insulin receptor	4218–4241 3′UTR	Transcript) 5′UCCUCAAAUUGACCAAUAGCUGCUGC 3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	7mer
			3844–3871 3′UTR	(Transcript) 5′UCAUCAUGAUCACUGAUUACUUGCUGCUC3′ (miRNA) 3′ AAGUUUUGUACUUAACGACGAC 5′	8mer

TargetScan Human, release 7.1 (www.targetscan.org) and Diana-TarBase v8 (http://carolina.imis.athena-innovation.gr/diana_tools/web/index.php?r=tarbasev8%2Findex) databases were used to predict the interaction sites between the transcripts and miR-424-5p