Table 3.
Basic demographic data of patients with hepatocellular carcinoma of different BCLC stages between surgical resection and non-surgical resection
| Variable | BCLC stage 0 (N = 66) | BCLC stage A (N = 865) | BCLC stage B (N = 575) | BCLC stage C (N = 810) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SR (N = 27) | Non-SR (n = 39) | P value | SR (N = 289) |
Non-SR (N = 576) | P value | SR (N = 164) |
Non-SR (N = 411) | P value | SR (N = 58) | Non-SR (N = 752) | P value | |
| Male | 21 (77.8) | 25 (64.1) | 0.235 | 225 (77.9) | 380 (66) | 0.001 | 135 (82.3) | 302 (73.5) | 0.025 | 45 (77.6) | 615 (81.8) | 0.428 |
| Age (years) | 55 (23–83) | 66 (24–85) | 0.001 | 59 (29–90) | 63 (28–92) | 0.0001 | 63 (30–88) | 64 (30–91) | 0.095 | 60 (25–87) | 61 (19–99) | 0.597 |
| Smoking | 10 (37) | 18 (46.2) | 0.461 | 92 (31.8) | 224 (38.9) | 0.042 | 71 (43.3) | 161 (39.2) | 0.363 | 20 (34.5) | 353 (46.9) | 0.067 |
| Alcohol use | 8 (29.6) | 14 (35.9) | 0.595 | 84 (29.1) | 199 (34.5) | 0.105 | 67 (40.9) | 151 (36.7) | 0.359 | 17 (29.3) | 328 (43.6) | 0.034 |
| HBV positive | 23 (85.2) | 21 (53.8) | 0.008 | 197 (68.2) | 402 (69.8) | 0.625 | 111 (67.7) | 303 (73.7) | 0.145 | 41 (70.7) | 560 (74.5) | 0.526 |
| HCV positive | 5 (18.5) | 9 (23.1) | 0.656 | 81 (28) | 172 (29.9) | 0.576 | 41 (25) | 131 (31.9) | 0.104 | 18 (31) | 239 (31.8) | 0.906 |
| Cirrhosis | 20 (74.1) | 23 (59) | 0.206 | 172 (59.5) | 339 (58.9) | 0.852 | 95 (57.9) | 239 (58.2) | 0.961 | 28 (48.3) | 479 (63.7) | 0.019 |
| Child-Pugh class A | 20 (74.1) | 23 (59) | 0.206 | 87 (30.1) | 190 (33.0) | 0.212 | 60 (36.6) | 165 (40.1) | 0.327 | 20 (34.5) | 289 (38.4) | 0.109 |
| Tumor size (cm) | 1.7 (1.0–2.0) | 1.6 (1.0–2.0) | 0.546 | 3.1 (1.0–5.0) | 2.7 (1.0–5.0) | < 0.001 | 8.1 (1.2–21) | 7.3 (1.2–21) | 0.002 | 9.5 (1.2–27) | 9.4 (1.2–27) | 0.850 |
| Tumor number | 1 (1–1) | 1 (1–1) | 1.000 | 1.4 (1–3) | 1.5 (1–3) | 0.089 | 2.1 (1–5) | 2.6 (1–11) | 0.003 | 2.7 (1–11) | 2.7 (1–11) | 0.890 |
| Mortality | 14 (51.9) | 23 (58.9) | 0.566 | 193 (66.80 | 279 (48.4) | 0.0001 | 158 (60.1) | 293 (48.7) | 0.002 | 28 (48.3) | 452 (60.1) | 0.077 |
| Median OS (months) | 71 (30–96) | 44 (8–81) | 53 (3–88) | 41 (1–96) | 41 (4–84) | 24 (1–76) | 38 (6–79) | 16 (1–66) | ||||
BCLC stage: Barcelona clinic liver cancer; SR: Surgical resection; HR: Hazard ratio; CI: Conference incidence; HBV: Hepatitis B virus; HCV: Hepatitis C virus; OS: Overall survival; Number (%); Mean or Median (range)