Table 4.
Variable | BCLC stage 0 (N = 43) | BCLC stage A (N = 578) | BCLC stage B (N = 327) | BCLC stage C (N = 116) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
SR (N = 27) |
Non-SR (N = 18) | P value | SR (N = 289) |
Non-SR (N = 289) |
P value | SR (N = 164) |
Non-SR (N = 163) | P value | SR (N = 58) |
Non-SR (N = 58) |
P value | |
Male | 21 (77.8) | 13 (72.2) | 0.671 | 208 (72) | 197 (68.2) | 0.318 | 135 (82.3) | 137 (84) | 0.675 | 45 (77.6) | 48 (82.8) | 0.485 |
Age (years) | 55 (23–83) | 59 (24–85) | 0.312 | 62 (29–90) | 60 (28–92) | 0.066 | 61 (30–88) | 62 (30–91) | 0.346 | 60 (25–87) | 60 (19–99) | 0.910 |
Smoking | 10 (37) | 10 (55.6) | 0.221 | 114 (39.4) | 95 (32.9) | 0.128 | 71 (43.3) | 57 (35.0) | 0.123 | 20 (34.5) | 16 (27.5) | 0.151 |
Alcohol use | 8 (29.8) | 7 (38.9) | 0.519 | 96 (33.2) | 86 (29.8) | 0.371 | 67 (40.9) | 62 (38.0) | 0.602 | 17 (29.3) | 13 (22.4) | 0.283 |
HBV positive | 25 (92.6) | 12 (66.7) | 0.260 | 200 (69.2) | 200 (69.2) | 1.000 | 111 (67.7) | 108 (66.3) | 0.784 | 41 (70.7) | 36 (62.1) | 0.085 |
HCV positive | 6 (22.2) | 5 (27.5) | 0.671 | 89 (30.8) | 76 (26.3) | 0.231 | 41 (25.0) | 44 (27.0) | 0.681 | 18 (31.0) | 11 (19.0) | 0.133 |
Cirrhosis | 20 (74.1) | 13 (72.2) | 0.891 | 177 (61.2) | 168 (58.1) | 0.445 | 95 (57.9) | 80 (49.1) | 0.109 | 28 (48.3) | 27 (46.5) | 0.873 |
Child–Pugh class A | 20 (74.1) | 13 (72.2) | 0.891 | 87 (30.1) | 92 (31.8) | 0.819 | 60 (36.6) | 68 (41.7) | 0.198 | 20 (34.5) | 18 (31.0) | 0.796 |
Tumor size (cm) | 1.7 (1.0–2.0) | 1.6 (1.0–2.0) | 0.812 | 2.8 (1.0–5.0) | 2.7 (1.0–5.0) | 0.289 | 7.7 (1.2–21) | 7.5 (1.2–21) | 0.105 | 9.5 (1.2–27) | 9.4 (1.2–27) | 0.885 |
Tumor number | 1 (1–1) | 1 (1–1) | 1.000 | 1.4 (1–3) | 1.5 (1–3) | 0.227 | 2.3 (1–5) | 2.5 (1–11) | 0.077 | 2.7 (1–11) | 2.7 (1–11) | 0.903 |
Mortality | 15 (55.6) | 12 (66.7) | 0.456 | 155 (53.6) | 183 (63.3) | 0.018 | 95 (57.9) | 103 (63.2) | 0.33 | 28 (48.3) | 55 (94.8) | 0.0001 |
Median OS (months) | 70 (30–96) | 43 (11–81) | 53 (3–88) | 46 (1–96) | 41 (4–84) | 20 (1–72) | 38(6–79) | 16 (1–62) |
BCLC stage: Barcelona clinic liver cancer; SR: Surgical resection; HR: Hazard ratio; CI: Conference incidence; HBV: Hepatitis B virus; HCV: Hepatitis C virus; OS: Overall survival; Number (%); Mean or Median (range)