Table 2.

Specifically designed antiviral peptides against enveloped viruses.

Peptide	Sequence	Target Virus	Mechanism proposed	Reference
P9	NGAICWGPCPTAFRQIGNCGHFKVRCCKIR	MERS-CoV, SARS-CoV, AIV	prevents endosomal acidification, which blocks membrane fusion	[37]
SARSWW-I	MWKTPTLKYFGGFNFSQIL	SARS-CoV	Entry inhibition	[29]
SARSWW-II	ATAGWTFGAGAALQIPFAMQMAY	SARS-CoV	Entry inhibition	[29]
EK1	SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL	SARS-CoV, MARS-CoV	Fusion inhibitor	[34]
YKYRYL	YKYRL	SARS-CoV	Block attachment to the host cells	[43]
RVFV-6	WNFFDWFSGLMSWFGGPLK	RVFV, Ebola virus, Andes virus and vesicular stomatitis virus	Fusion inhibitor	[47]
DN59	MAILGDTAWDFGSLGGVFTSIGKALHQVFGAIY	DENV	Viral membrane disruption	[64]
AVP-p	LNLFKKTINGLISDSLVIR	JUNV	Fusion inhibitor	[60]
NOVEL-1	NASDMEIKKVNKKIEEYIKKIEEVEKKLEEVNKK	NDV and IBV	Entry inhibition	[69]
NOVEL-2	VNKKIEEIDKKIEELNKKLEELEKKLEEVNKK	NDV and IBV	Entry inhibition	[69]
TLTTKLY	TLTTKLY	NDV	Entry inhibition	[67,72]
CTLTTKLYC	CTLTTKLYC	NDV	Entry inhibition	[67,72]
TP1	SWLVNRDWFHDLNLPWTGSSAGTWQ	TMUV	Block attachment to the host cells	[84,85]
TP2	MVALGDTAWDFGSVGGVLTSIGKGIHQVFGSAFKSL	TMUV	Block attachment to the host cells and viral membrane disruption	[84,85]
NDFRSKT	NDFRSKT	AIV	Block attachment to the host cells	[86,87]
CNDFRSKTC	CNDFRSKTC	AIV	Block attachment to the host cells	[85,86]