Table 4.
Univariate and multivariate analyses of the factors affecting overall survival.
| Parameter | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P value | Hazard ratio | 95% CI | P value | |
| Necrosis type (liquefactive/coagulative) | 0.623 | 0.450–0.863 | 0.004 | 0.596 | 0.426–0.834 | 0.003 |
| Sex (Male/Female) | 1.354 | 0.823–2.226 | 0.231 | |||
| Age (>60 years/<60 years) | 1.232 | 0.879–1.727 | 0.226 | |||
| Hepatitis (present/absent) | 0.944 | 0.604–1.474 | 0.799 | |||
| Liver cirrhosis (present/absent) | 0.607 | 0.439–0.840 | 0.002 | 0.664 | 0.471–0.936 | 0.019 |
| Child-Pugh classification (B/A) | 0.194 | 0.126–0.300 | 0.000 | 0.210 | 0.134–0.329 | 0.000 |
| Barcelona Clinic Liver Cancer (stage C/stage B) | 0.780 | 0.510–1.193 | 0.250 | |||
| Maximum diameter (>10 cm/<10 cm) | 0.942 | 0.683–1.299 | 0.715 | |||
| Pseudocapsule (present/absent) | 0.994 | 0.702–1.408 | 0.972 | |||
| Alpha-fetoprotein (>400 ng/ml/<400 ng/ml) | 0.793 | 0.571–1.099 | 0.163 | |||
| Location (left lobe/right lobe) | 0.698 | 0.486–1.005 | 0.052 | 0.675 | 0.461–0.989 | 0.044 |
| Portal vein tumor thrombus (present/absent) | 0.700 | 0.501–0.978 | 0.036 | 0.910 | 0.629–1.315 | 0.615 |
| Arteriovenous fistula (present/absent) | 0.624 | 0.421–0.925 | 0.018 | 0.729 | 0.481–1.104 | 0.136 |
| Other treatments (present/absent) | 0.757 | 0.512–1.121 | 0.163 | |||
CI – confidence interval. P<0.05 was considered a statistically significant difference.