Table 3.
Changes from baseline to 9 weeks in parameters of cardiopulmonary capacity in patients with diabetes mellitus (adjusted for baseline)
| CPET parameters | With DM | |||
|---|---|---|---|---|
| Δ 9 week–baseline [95% CI] | Difference [95% CI] | p | ||
| HCTR-DM | UC-DM | |||
| Exercise time (s) | 35.9 [21.0; 50.8] | 23.9 [9.4; 38.4] | 12.0 [− 15.1; 39.1] | 0.666 |
| VO2 peak (ml/min/kg) | 0.40 [− 0.18; 0.98] | − 0.15 [− 0.72; 0.41] | 0.55 [− 0.50; 1.61] | 0.529 |
| Percent-predicted VO2 (%) | 1.69 [− 0.49; 3.86] | − 2.04 [− 4.16; 0.09] | 3.73 [− 0.22; 7.66] | 0.072 |
| VAT (ml/kg/min) | − 0.22 [− 1.06; 0.62] | 0.16 [− 0.73; 1.05] | − 0.38 [− 1.98; 1.21] | 0.926 |
| Ventilation at rest (l/min) | − 0.38 [− 1.07; 0.30] | − 0.04 [− 0.70; 0.63] | − 0.34 [− 1.60; 0.91] | 0.892 |
| Ventilation on peak exercise (l/min) | 1.54 [− 0.44; 3.52] | 0.54 [− 1.37; 2.46] | 1.00 [− 2.60; 4.60] | 0.891 |
| Breathing rate at rest (1/min) | 0.11 [− 0.61; 0.83] | 0.30 [− 0.40; 0.99] | − 0.19 [− 1.50; 1.12] | 0.983 |
| Breathing rate on peak exercise (1/min) | 0.77 [− 0.02; 1.55] | − 0.25 [− 1.01; 0.51] | 1.02 [− 0.42; 2.45] | 0.263 |
| VE/VCO2 slope | 1.42 [− 0.25; 3.09] | − 0.10 [− 1.74; 1.54] | 1.52 [− 1.55; 4.59] | 0.579 |
CI confidence interval, CPET Cardiopulmonary Exercise Testing, HCTR-DM patients in hybrid comprehensive telerehabilitation arm with heart failure and diabetes, HCTR-nonDM patients in hybrid comprehensive telerehabilitation arm with heart failure and without diabetes, VO2 peak peak oxygen uptake, UC-DM patients in usual care arm with heart failure and diabetes, UC-nonDM patients in usual care arm with heart failure and without diabetes, VAT ventilatory anaerobic threshold, VE/VCO2 slope slope of ventilatory equivalent for carbon dioxide