. 2021 May 14;19:71. doi: 10.1186/s12958-021-00751-y

Table 1.

Characteristics of included women

	Non-PE	PE	p value	Subgroups^a			p value
	Non-PE	PE	p value	A	B	C	p value
Number	54	275	–	53	64	53	–
Clinical characteristics
Mean age (years)	27.61 ± 4.52	30.16 ± 5.53	< 0.001	31.70 ± 5.51	30.27 ± 6.00	31.28 ± 5.12	0.180
Gestation week (weeks)	37.96 ± 3.71	36.65 ± 3.68	0.012	37.19 ± 2.20	37.31 ± 2.87	34.53 ± 4.19^ab	< 0.001
Primipara (%)	35 (64.8)	146 (53.1)	0.113	25 (47.2)	38(59.4)	27(50.9)	0.395
Multipara (%)	19 (35.2)	129 (46.9)	0.113	28 (52.8)	26 (40.6)	26 (49.1)	0.395
Mode of delivery
Spontaneously (%)	38 (70.4)	24 (8.7)	< 0.001	6 (13)	1 (1.7)	1 (2.4)	0.038
Caesarean section (%)	14 (29.6)	232 (91.3)	< 0.001	46 (87)	59 (98.3)	42 (97.6)	0.038
Laboratory findings
SBP (mmHg)	113.46 ± 9.67	146.34 ± 18.24	< 0.001	140.76 ± 14.23	143.67 ± 17.72	155.40 ± 19.53^ab	< 0.001
DBP (mmHg)	70.5 ± 8.53	95.44 ± 13.68	< 0.001	91.30 ± 9.83	93.60 ± 13.10	104.15 ± 14.42^ab	< 0.001
ALT (U/L)	14.58 ± 13.34	34.59 ± 64.46	< 0.001	37.79 ± 93.46	24.51 ± 25.83	43.62 ± 78.85	0.055
AST (U/L)	18.37 ± 6.89	35.82 ± 49.85	< 0.001	35.70 ± 67.53	30.01 ± 40.16	43.63 ± 64.72	0.191
Albumin (g/L)	37.44 ± 4.55	34.15 ± 4.92	< 0.001	36.63 ± 3.62	34.23 ± 4.38^a	31.38 ± 4.52^ab	< 0.001
Uric acid (μmol/L)	315.72 ± 67.35	424.38 ± 108.67	< 0.001	352.09 ± 82.85	419.66 ± 119.40^a	460.14 ± 99.80^a	< 0.001
Creatinine (μmol/L)	45.22 ± 6.23	62.53 ± 46.85	< 0.001	46.44 ± 8.46	58.53 ± 18.95	72.52 ± 41.09^ab	< 0.001
Proteinuria (mg/24 h)	–	–	–	136.27 ± 89.39	884.29 ± 538.33	6246.13 ± 5099.54^ab	< 0.001

ALT Alanine aminotransferasem, AST Aspartate aminotransferase, DBP Diastolic Blood Pressure; SBP: Systolic Blood Pressure; a: compared with A group, p < 0.05; b: compared with B group, p < 0.05

Subgroups^a: A: 24-h urinary protein < 0.3 g; B:24-h urinary protein 0.3 ~ 2 g; C:24-h urinary protein ≧ 2 g