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. 2021 May 7;7(5):e06892. doi: 10.1016/j.heliyon.2021.e06892

Table 8.

Advantages and disadvantages of the Ti6Al4V alloy.

Advantages Disadvantages
  • Excellent biocompatibility when contact with bone and tissues is required [90].

  • Good mechanical properties and high corrosion resistance [91].

  • Most widely used alloy in the additive manufacturing of orthopedic implants [90].

  • High probability of promoting osteoblast maturation, as an osteogenic environment is established when cells similar to osteoblasts are cultured on its substrate, which could improve bone formation [92].

  • Low wear resistance and fatigue strength [93].

  • Formation of bacterial biofilms on the implant's surface [86].

  • Risk of causing health problems such as Alzheimer's disease, neuropathies, and osteomalacia (5), as well as allergic reactions, due to the release of Al and V ions [94].

  • Risk of leading to implant loosening due to its high Young's modulus [84].