Table 7.
Ternary Diagram | Formulation | SEDDS Formulation Composition (%v/v) | Maximum ELQ-331 Conc. Observed by HPLC Analysis (mg/mL) | Prepared ELQ-331 Conc. (mg/mL) | Observation upon 1 to 100 Dilution with Water |
---|---|---|---|---|---|
A | 1 | 28.57 % Caproyl 90 + 47.14% Labrasol + 24.29% Tween 20 | 76.60 | 60.00 | Formed a cloudy emulsion |
B | 2 | 28.57% Capmul MCM + 35.72% Labrasol + 35.71% Tween 20 | 56.20 | 45.00 | Formed slightly cloudy emulsion |
C | 3 | 25.00% Capmul MCM + 37.50% PEG 400 + 37.50% Tween 20 | 48.90 | 40.00 | Formed a clear emulsion, with blue appearance |