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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Pharm Dev Technol. 2020 Feb 12;25(5):625–639. doi: 10.1080/10837450.2020.1725893

Table 7.

Composition and assay results of ELQ-331 SEDDS formulations prepared from each pseudo-ternary phase diagram.

Ternary Diagram Formulation SEDDS Formulation Composition (%v/v) Maximum ELQ-331 Conc. Observed by HPLC Analysis (mg/mL) Prepared ELQ-331 Conc. (mg/mL) Observation upon 1 to 100 Dilution with Water
A 1 28.57 % Caproyl 90 + 47.14% Labrasol + 24.29% Tween 20 76.60 60.00 Formed a cloudy emulsion
B 2 28.57% Capmul MCM + 35.72% Labrasol + 35.71% Tween 20 56.20 45.00 Formed slightly cloudy emulsion
C 3 25.00% Capmul MCM + 37.50% PEG 400 + 37.50% Tween 20 48.90 40.00 Formed a clear emulsion, with blue appearance