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Effect of RUP with or without wortmannin on ISO-induced changes in myocardial contents of (A) PAF (B) IL-6 (C) IL-23, and (D) TGF-β. Each value represents the mean of six experiments and error bars represent SD. Statistical analysis was done using One way ANOVA followed by Tukey’s post-hoc test where a p < 0.05 vs. normal, b p < 0.05 vs. ISO, c p < 0.05 vs. RUP.
