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Effect of RUP with or without wortmannin on ISO-induced changes in myocardial contents of (A) p-STAT 3 and (B) pAkt/total Akt ratio. Each value represents the mean of six experiments and error bars represent SD. Statistical analysis was done using One way ANOVA followed by Tukey’s post-hoc test where a p < 0.05 vs. normal, b p < 0.05 vs. ISO, c p < 0.05 vs. RUP.
