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Effect of RUP with or without wortmannin on ISO-induced changes in myocardial content of (A) atrogin-1 as well as the protein expression of (B) troponin I and (C) troponin T. Each value represents the mean of six experiments and error bars represent SD. Statistical analysis was done using One way ANOVA followed by Tukey’s post-hoc test where a p <0.05 vs. normal, b p <0.05 vs. ISO, c p <0.05 vs. RUP.
