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Effect of RUP with or without wortmannin on ISO-induced changes in myocardial contents of (A) Bax and (B) Bcl2 in addition to (C) Bax/Bcl2 ratio and (D) caspase-3 activity. Each value represents the mean of six experiments and error bars represent SD. Statistical analysis was done using One way ANOVA followed by Tukey’s post-hoc test where a p < 0.05 vs. normal, b p < 0.05 vs. ISO, c p < 0.05 vs. RUP.
