Table 4.

Hierarchical Multiple Logistic Regression Analysis of the Factors Associated with Effectiveness of Sertraline or Venlafaxine

n=132	Model 1		Model 2
Independent Valuables	Odds Ratio	p	Odds Ratio	p
Age	1.01 (0.98–1.03)	0.548	1.01 (0.99–1.04)	0.337
Gender (Female=1, Male=0)	0.98 (0.38–2.51)	0.969	1.02 (0.37–2.80)	0.977
BMI	0.96 (0.85–1.08)	0.465	0.94 (0.83–1.07)	0.361
Smoking	1.76 (0.57–5.45)	0.325	1.98 (0.60–6.51)	0.261
CES-D	1.02 (0.97–1.07)	0.404	1.02 (0.97–1.07)	0.366
STAI-state	1.00 (0.94–1.06)	0.931	1.02 (0.95–1.08)	0.610
STAI-trait	0.98 (0.92–1.04)	0.535	0.96 (0.90–1.03)	0.251
Current use of benzodiazepines	0.86 (0.33–2.20)	0.749	0.93 (0.34–2.55)	0.886
Fatigue	1.81 (0.66–4.97)	0.253	2.01 (0.66–6.16)	0.221
Dizziness or vertigo	0.66 (0.21–2.06)	0.471	0.67 (0.20–2.25)	0.514
Headache	1.73 (0.57–5.25)	0.335	1.40 (0.43–4.57)	0.582
Non-headache pain	1.86 (0.56–6.12)	0.310	1.64 (0.46–5.83)	0.445
Numbness	0.44 (0.13–1.55)	0.203	0.51 (0.13–2.05)	0.346
Nausea	0.64 (0.19–2.09)	0.457	0.79 (0.22–2.78)	0.709
Chest tightness	0.67 (0.22–2.07)	0.489	0.71 (0.21–2.37)	0.574
Palpitation	1.19 (0.39–3.69)	0.758	1.03 (0.30–3.51)	0.962
Chronic cough or globus syndrome	1.02 (0.32–3.28)	0.976	0.97 (0.25–3.80)	0.967
Breathlessness	1.40 (0.24–8.23)	0.710	1.64 (0.24–11.2)	0.616
Anorexia	0.78 (0.28–2.14)	0.628	0.60 (0.20–1.79)	0.357
Insomnia	0.68 (0.24–1.95)	0.473	0.86 (0.26–2.81)	0.801
Diminished motivation	1.02 (0.37–2.85)	0.965	0.88 (0.28–2.75)	0.822
Suicidal ideation	6.91 (1.31–36.4)	0.022*	3.30 (0.54–20.2)	0.197
High-3HB (≥80 μmol/L)			10.0 (2.49–40.3)	0.001**
Predictive accuracy (%)	72.0		74.2
−2 Log likelihood	151.8		134.7
p value for Δ-2 Log likelihood change	<0.001***

Notes: 95% confidence intervals are included in parentheses. *p<0.05, **p<0.01, ***p<0.001.