Table 4. Survey of Autonomic Symptoms (SAS) questionnaire to diagnose the involvement of different organs and systems in dysautonomia.
| Symptoms/Health Problem | Have you had any of these symptoms in the last 6 months? 1- Yes; 2- No | How severe is this symptom? Scale of 1 to 5 (used if symptoms are present) |
|---|---|---|
| 1-Darkened vision? | 1 or 2 | 1 – 5 |
| 2-Dry mouth or dry eyes? | ||
| 3-Pallor or cyanosis? | ||
| 4-Feeling cold in some regions of the body? | ||
| 5-Reduced feet sweating compared to the rest of the body? | ||
| 6-Reduced or absent feet sweating after exercising or in hot weather? | ||
| 7-Increased hand sweating compared to the rest of the body? | ||
| 8-Nausea, vomiting or gas after light meals? | ||
| 9-Diarrhea (>3 bowel movements per day)? | ||
| 10-Persistent constipation? | ||
| 11-Loss of urine? | ||
| 12-Erection issues? |
Source: Adapted.61 The presence of 3 or more symptoms resulted in 95% sensitivity and 65% specificity, while the presence of 7 or more points determined 60% sensitivity and 90% specificity. Gastrointestinal symptoms were less correlated with other indexes.