Fig. 3.

Forest plot with pairwise comparisons of guselkumab Q8W vs all comparators for ACR 20

Comparisons are shown in terms of RRs and 95% CrIs. Treatments are grouped by therapeutic class. The vertical dotted line represents a RR of 1.00. The probability that guselkumab Q8W is better is also shown for each comparator. For the full league table of results, please consult the supplementary appendix, available at Rheumatology online. ACR: American College of Rheumatology; BIW: biweekly; CrI: credible interval; CTLA-4i: cytotoxic T-lymphocyte-associated protein 4; GUS: guselkumab; IL-17Ai: interleukin-17A inhibitor; IL-12/23i: interleukin-12/23 inhibitor; IL-23i: interleukin-23 inhibitor; IV: intravenous; LD: loading dose; Q2W: every 2 weeks; Q4W: every 4 weeks; Q8W: every 8 weeks; RR: relative risk; TNFi: tumor necrosis factor inhibitor.