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(A) Normalization score for the quantification of steroids in conditioned brains treated with DMSO or finasteride (10 μM). n = 5 set of 10 brains per condition. *P < 0.05, by Student’s t test. (B) Partial neurosteroidogenesis pathways. Finasteride blocked the rate-limiting enzyme 5α-reductase, causing accumulation of upstream neurosteroid species.
