Appendix 1—table 2. Age stratified baseline prevalence of health outcomes.
| Baseline Prevalence | |||
|---|---|---|---|
| 1–11 months | 12–23 months | 24–48 months | |
| Any bacterial or protozoan infection | |||
| All children | 108/208 (52%) | 179/221 (81%) | 277/297 (93%) |
| Control | 57/109 (52%) | 101/119 (85%) | 143/152 (94%) |
| Intervention | 51/99 (52%) | 78/102 (76%) | 134/145 (92%) |
| Any STH infection | |||
| All children | 30/185 (16%) | 89/203 (44%) | 171/277 (62%) |
| Control | 17/93 (18%) | 50/112 (45%) | 94/144 (65%) |
| Intervention | 13/92 (14%) | 39/91 (43%) | 77/133 (58%) |
| Diarrhea | |||
| All children | 37/258 (14%) | 52/264 (20%) | 36/427 (8.4%) |
| Control | 19/138 (14%) | 27/146 (18%) | 20/234 (8.6%) |
| Intervention | 18/120 (15%) | 25/118 (21%) | 16/193 (8.3%) |
| Any bacterial infection | |||
| All children | 94/208 (45%) | 150/221 (68%) | 229/297 (77%) |
| Intervention | 53/109 (49%) | 89/119 (75%) | 117/152 (77%) |
| All children | 41/99 (41%) | 61/102 (60%) | 112/145 (77%) |
| Shigella | |||
| All children | 19/208 (9.1%) | 97/221 (44%) | 192/297 (65%) |
| Control | 10/109 (9.2%) | 57/119 (48%) | 101/152 (66%) |
| Intervention | 9/99 (9.1%) | 40/102 (39%) | 91/145 (63%) |
| ETEC | |||
| All children | 47/208 (23%) | 81/221 (37%) | 90/297 (30%) |
| Control | 25/109 (23%) | 45/119 (38%) | 43/152 (28%) |
| Intervention | 22/99 (22%) | 36/102 (35%) | 47/145 (32%) |
| Campylobacter | |||
| All children | 22/208 (11%) | 19/221 (8.6%) | 16/297 (5.4%) |
| Control | 14/109 (13%) | 13/119 (11%) | 10/152 (6.6%) |
| Intervention | 8/99 (8.1%) | 6/102 (5.9%) | 6/145 (4.1%) |
| C. difficile | |||
| All children | 23/208 (11%) | 10/221 (4.5%) | 2/297 (0.67%) |
| Control | 13/109 (12%) | 7/119 (5.9%) | 2/152 (1.3%) |
| Intervention | 10/99 (10%) | 3/102 (2.9%) | 0/145 (0.0%) |
| E. coli o157 | |||
| All children | 6/208 (2.9%) | 10/221 (4.5%) | 15/297 (5%) |
| Control | 4/109 (3.7%) | 3/119 (2.5%) | 6/152 (4%) |
| Intervention | 2/99 (2%) | 7/102 (6.9%) | 9/145 (6.2%) |
| STEC | |||
| All children | 3/208 (1.4%) | 7/221 (3.2%) | 3/297 (1%) |
| Control | 0/109 (0.0%) | 1/119 (0.84%) | 2/152 (1.3%) |
| Intervention | 3/99 (3%) | 6/102 (5.9%) | 1/145 (0.69%) |
| Y. enterocolitica | |||
| All children | 0/208 (0.0%) | 1/221 (0.45%) | 0/297 (0.0%) |
| Control | 0/109 (0.0%) | 0/119 (0.0%) | 0/152 (0.0%) |
| Intervention | 0/99 (0.0%) | 1/102 (0.98%) | 0/145 (0.0%) |
| V. cholerae | |||
| All children | 0/208 (0.0%) | 0/221 (0.0%) | 0/297 (0.0%) |
| Control | 0/109 (0.0%) | 0/119 (0.0%) | 0/152 (0.0%) |
| Intervention | 0/99 (0.0%) | 0/102 (0.0%) | 0/145 (0.0%) |
| Any Protozoa | |||
| All children | 36/208 (17%) | 120/221 (54%) | 223/297 (75%) |
| Control | 14/109 (13%) | 68/119 (57%) | 114/152 (75%) |
| Intervention | 22/99 (22%) | 52/102 (51%) | 109/145 (75%) |
| Giardia | |||
| All children | 28/208 (13%) | 119/221 (54%) | 219/297 (74%) |
| Control | 12/109 (11%) | 67/119 (56%) | 113/152 (74%) |
| Intervention | 16/99 (16%) | 52/102 (51%) | 106/145 (73%) |
| Cryptosporidium | |||
| All children | 10/208 (4.8%) | 9/221 (4.1%) | 5/297 (1.7%) |
| Control | 2/109 (1.8%) | 5/119 (4.2%) | 1/152 (0.66%) |
| Intervention | 8/99 (8.1%) | 4/102 (3.9%) | 4/145 (2.8%) |
| E. histolytica | |||
| All children | 1/208 (0.48%) | 0/221 (0.0%) | 3/297 (1%) |
| Control | 0/109 (0.0%) | 0/119 (0.0%) | 0/152 (0.0%) |
| Intervention | 1/99 (1%) | 0/102 (0.0%) | 3/145 (2.1%) |
| Any virus | |||
| All children | 36/208 (17%) | 34/221 (15%) | 33/297 (11%) |
| Control | 15/109 (14%) | 19/119 (16%) | 19/152 (13%) |
| Intervention | 21/99 (21%) | 15/102 (15%) | 14/145 (9.7%) |
| Norovirus GI/GII | |||
| All children | 27/208 (13%) | 25/221 (11%) | 23/297 (7.7%) |
| Control | 12/109 (11%) | 14/119 (12%) | 12/152 (7.9%) |
| Intervention | 15/99 (15%) | 11/102 (11%) | 11/145 (7.6%) |
| Adenovirus 40/41 | |||
| All children | 7/208 (3.4%) | 7/221 (3.2%) | 8/297 (2.7%) |
| Control | 4/109 (3.7%) | 3/119 (2.5%) | 6/152 (4%) |
| Intervention | 3/99 (3%) | 4/102 (3.9%) | 2/145 (1.4%) |
| Rotavirus A | |||
| All children | 3/208 (1.4%) | 5/221 (2.3%) | 2/297 (0.67%) |
| Control | 0/109 (0.0%) | 2/119 (1.7%) | 1/152 (0.66%) |
| Intervention | 3/99 (3%) | 3/102 (2.9%) | 1/145 (0.69%) |
| Coinfection, ≥2 GPP pathogens | |||
| All children | 48/208 (23%) | 118/221 (53%) | 203/297 (68%) |
| Control | 23/109 (21%) | 69/119 (58%) | 104/152 (68%) |
| Intervention | 25/99 (25%) | 49/102 (48%) | 99/145 (68%) |
| Trichuris | |||
| All children | 20/185 (11%) | 69/203 (34%) | 150/277 (54%) |
| Control | 10/93 (11%) | 38/112 (34%) | 82/144 (57%) |
| Intervention | 10/92 (11%) | 31/91 (34%) | 68/133 (51%) |
| Ascaris | |||
| All children | 21/185 (11%) | 53/203 (26%) | 81/277 (29%) |
| Control | 12/93 (13%) | 33/112 (29%) | 47/144 (33%) |
| Intervention | 9/92 (9.8%) | 20/91 (22%) | 34/133 (26%) |
| Coinfection, ≥2 STH | |||
| All children | 11/185 (6%) | 33/203 (16%) | 60/277 (22%) |
| Control | 5/93 (5.4%) | 21/112 (19%) | 35/144 (24%) |
| Intervention | 6/92 (6.5%) | 12/91 (13%) | 25/133 (19%) |
| Number of GPP infections | |||
| All children | 0.94 (1.1) | 1.8 (1.2) | 1.9 (0.95) |
| Control | 0.88 (1.1) | 1.8 (1.1) | 2 (0.93) |
| Intervention | 1 (1.1) | 1.7 (1.3) | 1.9 (0.98) |
| Number of STH infections | |||
| All children | 0.23 (0.55) | 0.61 (0.75) | 0.86 (0.76) |
| Control | 0.24 (0.54) | 0.64 (0.78) | 0.9 (0.76) |
| Intervention | 0.23 (0.56) | 0.57 (0.72) | 0.8 (0.76) |
Data presented n/N (%) or mean (standard deviation). All bacterial, protozoan, and viral pathogens were measured using the Luminex Gastrointestinal Pathogen panel. STH were measured using the Kato-Katz method. Diarrhea was measured via caregiver report in household surveys.