Appendix 1—table 7. Sensitivity analysis assessing the impact of reported deworming on STH effect estimates 12 and 24 months after the intervention.
| 12-month Prevalence ratio | 24-month Prevalence ratio | |||||
|---|---|---|---|---|---|---|
| Main analysis, all children* | Adjusted for reported deworming † | Restricted to children dewormed at baseline ‡ | Main analysis, all children* | Adjusted for reported deworming † | Adjusted for time since deworming§ | |
| n = 1239 | n = 1239 | n = 1031 | n = 1161 | n = 1161 | N = 1159 | |
| Any STH infection | 1.11 (0.89–1.38) | 1.09 (0.87–1.35) | 1.06 (0.84–1.33) | 0.95 (0.77–1.17) | 0.93 (0.77–1.16) | 0.93 (0.75–1.14) |
| Trichuris | 1.01 (0.79–1.28) | 0.98 (0.77–1.24) | 0.96 (0.74–1.23) | 0.86 (0.67–1.10) | 0.85 (0.66–1.08) | 0.86 (0.67–1.09) |
| Ascaris | 1.33 (0.92–1.93) | 1.30 (0.90–1.88) | 1.30 (0.87–1.94) | 0.83 (0.54–1.27) | 0.84 (0.55–1.29) | 0.78 (0.51–1.18) |
| Coinfection,≥2 STH | 1.17 (0.76–1.79) | 1.12 (0.73–1.71) | 1.16 (0.73–1.85) | 0.63 (0.37–1.07) | 0.63 (0.37–1.08) | 0.60 (0.35–1.03) |
All effect estimates are presented as prevalence ratios (ratio of ratios) with 95% confidence intervals and estimated using generalized estimating equations to fit Poisson regression models with robust standard errors. All models adjusted for child age, sex, caregiver education level, and household wealth.
*Analysis includes all children regardless of caregiver-reported deworming status.
†Analysis is adjusted for reported deworming status. Effect estimates at 12 month are adjusted for baseline deworming confirmation, effect estimates at 24 month are adjusted for baseline and/or 12 month deworming confirmation.
‡Analysis is restricted to children whose caregivers confirmed baseline deworming.
§ Adjusted for time between 12 month deworming and 24 month sample collection, time broken into three intervals: 0–3 months, 4–6 months, and >6 months. The NDC performed 12 month deworming activities at the end of the 12 month phase instead of concurrent to 12 month sample collection resulting in some variation in the amount of time between 12 month deworming and 24 month sample collection among participants. All samples collected during 12 month phase were collected >6 months after deworming and no adjustment for time since deworming was made.