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. 2021 Apr 9;10:e62278. doi: 10.7554/eLife.62278

Appendix 1—table 8. Sensitivity analysis assessing impact of independent upgrading of control sanitation facilities on effect estimates.

12-month adjusted prevalence ratio 24 month adjusted prevalence ratio
Main analysis, all children* Excluding controls with upgraded sanitation† Main analysis, all children* Excluding controls with upgraded sanitation†
Any bacterial or protozoan infection 1.04 (0.94–1.15), n = 1510 1.05 (0.95–1.16), n = 1491 0.99 (0.91–1.09), n = 1536 1.00 (0.91–1.10), n = 1502
Any STH infection 1.11 (0.89–1.38), n = 1239 1.11 (0.89–1.38), n = 1225 0.95 (0.77–1.17), n = 1161 0.94 (0.76–1.16), n = 1148
Diarrhea 1.69 (0.89–3.21), n = 1594 1.76 (0.91–3.39), n = 1575 0.84 (0.47–1.51), n = 1502 0.81 (0.45–1.48), n = 1471

All effect estimates are presented as prevalence ratios (ratio of ratios) with 95% confidence intervals and estimated using generalized estimating equations to fit Poisson regression models with robust standard errors. All infection outcomes are adjusted for child age and sex, caregiver’s education, and household wealth index, and the diarrhea outcome is also adjusted for baseline presence of a drop-hole cover and reported use of a tap on compound grounds as primary drinking water source.

* Results represent effect estimates for the main analyses which included control children irrespective of whether their latrines had been independently upgraded (results also presented in Table 2 in main text).

Results from sensitivity analyses which exclude control children living in compounds that independently upgraded their latrines to be similar to the intervention.