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. 2021 May 6;48(1):121. doi: 10.3892/ijmm.2021.4954

Figure 7.

Figure 7

LBP inhibits the release of inflammatory factors and reduces neuroinflammation in OVX model mice. (A and B) Immunohistochemical staining was used to analyze the expression of TLR4, MyD88, NF-κB, IL-6, IL-1β and TNF-α in the hippocampal CA1 and CA3 regions. Scale bar, 20 µm. (C and D) Positive staining area in the CA1 and CA3 regions for TLR4, MyD88, NF-κB, IL-6, IL-1β and TNF-α expression in OVX model mice. Data were analyzed using a one-way ANOVA and an LSD post hoc test. *P<0.05 vs. the OVX group (n=5/group). LBP, Lycium barbarum polysaccharide; OVX, ovariectomy; TLR, Toll-like receptor; MyD88, myeloid differentiation primary response 88.