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. 2021 May 6;2021:9952578. doi: 10.1155/2021/9952578

Table 3.

Anti-inflammatory functions.

Biomarkers Model Reference
Declined NO, PGE2, TNF-α, and other cytokine release activities RAW 264.7 cells Dong et al. [44]; Ma et al. [41]
Reduced CD68 and F4/80 mRNA levels Raw 264.7 Hoo et al. [45]
Enhanced SOD and TGF-β contents Type 2 diabetes mellitus rat model EIsherbiny et al. [40]
Reduced IκBα and NF-κB p65 protein translational levels and alleviated insulin resistance db/db obese mice Hoo et al. [45]
Alleviated inflammatory responses and cytokine levels via attenuating Erk1/2 and NF-κB pathways Hepatocyte cell line; HUVEC Figarola et al. [46]; Kim et al. [47]; Cheng et al. [48]; Xu et al. [49]