Table 1.

Provides the rate and drug releases process for all core-shell.

		Loaded drug (mg/g)	Released drug (mg)	Average rate of released (mg/h)	Duration time (h)	% Released
pH ∼ 3.0
CSP		400	380	15.8	∼24	95
CDSP	Outer shell	200	198	11.64	∼17	99
	Inner shell	200	192	9.6	∼20	96
Total		400	390	∼ 10.4	∼ 37	97.5
CTSP	Outer shell	150	150	8.33	∼18	100
	Middle shell	150	148	6.72	∼22	98.6
	Inner shell	100	98	4.9	∼20	98
Total		400	396	∼ 6.6	∼ 60	99
pH ∼ 5.4
CSP		400	340	8.5	∼ 40	85
CDSP	Outer shell	200	190	7.0	∼ 27	95
	Inner shell	200	185	7.4	∼ 25	92.5
Total		400	375	∼ 7.2	∼ 52	93.75
CTSP	Outer shell	150	150	6.8	∼22	100
	Middle shell	150	147	5.65	∼26	98
	Inner shell	100	90	4.0	∼24	90
Total		400	387	∼ 5.4	∼72	96.75
pH ∼ 7.4
CSP		400	320	6.6	∼48	80
CDSP	Out shell	200	170	6.1	∼28	85
	Inner shell	200	150	5.0	∼30	75
Total		400	320	∼5.5	∼58	80
CTSP	Out shell	150	145	5.0	∼28	96
	Middle shell	150	140	4.0	∼35	93
	Inner shell	100	75	2.5	∼30	75
Total		400	360	∼3.9	∼93	90