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. 2021 May 14;12(5):493. doi: 10.1038/s41419-021-03773-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A, B Representative pictures of cell migration (A) and invasion (B) in H292 and A549cells analyzed by transwell assay. Scale bars, 100 μm. C Representative pictures of cell apoptosis after treatment with cisplatin for 24 h analyzed by TUNEL staining (green). Cells were counterstained with DAPI. Scale bars, 20 μm. D Cell migration was assessed by culturing HUVECs with conditioned medium collected from the indicated NSCLC cells. Scale bars, 100 μm. E Representative images of tubule formation by HUVECs cultured in Matrigel-coated plates with conditioned medium collected from the indicated NSCLC cells. Scale bars, 50 μm.