Table 1.
Univariate and multivariate analysis of different prognostic parameters in patients with NSCLC by Cox-regression analysis.
Variable | Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|---|
Regression coefficient (SE) | HR | 95% CI | P Value | HR | 95% CI | P Value | |
Gender | −0.335 (0.381) | 0.715 | 0.339–1.510 | 0.380 | |||
Age (years) | −0.692 (0.391) | 0.501 | 0.232–1.078 | 0.077 | |||
Smoke | 0.200 (0.373) | 1.221 | 0.588–2.536 | 0.592 | |||
T classification | 0.563 (0.216) | 1.756 | 1.149–2.683 | 0.009 | ─ | ─ | 0.174 |
N classification (N0 vs. N1 + N2) | 1.188 (0.403) | 3.282 | 1.489–7.233 | 0.003 | 4.302 | 1.914–9.667 | <0.001 |
Clinical stage (I + II vs. III + IV) | 1.201 (0.387) | 3.324 | 1.556–7.103 | 0.002 | ─ | ─ | 0.821 |
miR-135b (low vs. high) | 1.226 (0.419) | 3.409 | 1.501–7.742 | 0.003 | 4.822 | 1.978–11.757 | 0.001 |