Table 1.
Total number of OXT, AVP, and OXT + AVP neurons in the hypothalamus nuclei during development.
| OXT | E16.5 | PN0 | PN7 | Adult |
|---|---|---|---|---|
| BNST | 0.00 | 2.00 ± 2.00 | 16.00 ± 9.94 | 100.00 ± 36.46 |
| PVN | 24.50 ± 14.22 | 123.75 ± 33.62 | 131.25 ± 70.70 | 461.25 ± 20.60 |
| SON | 116.75 ± 12.60 | 33.00 ± 13.37 | 83.50 ± 50.49 | 216.00 ± 44.67 |
| VMPO | 0.00 | 6.25 ± 2.46 | 3.25 ± 3.25 | 8.75 ± 4.84 |
| RCH | 99.25 ± 11.92 | 63.25 ± 16.85 | 70.75 ± 8.62 | 101.75 ± 28.05 |
| ADPN | 0.00 | 0.00 | 17.75 ± 14.79 | 75.00 ± 28.67 |
| PeVN | 0.00 | 30.25 ± 18.22 | 50.50 ± 31.62 | 123.50 ± 45.17 |
| AN | 0.00 | 37.5 ± 15.76 | 11.50 ± 5.45 | 164.75 ± 18.28 |
| SCH | 0.00 | 3.67 ± 1.61 | 0.67 ± 0.58 | 4.00 ± 1.78 |
| MeA | 0.00 | 0.25 ± 0.25 | 0.25 ± 0.25 | 0.50 ± 0.50 |
| AVP | E16.5 | PN0 | PN7 | Adult |
|---|---|---|---|---|
| BNST | 0.00 | 2.75 ± 1.80 | 9.50 ± 3.80 | 1.5 ± 0.65 |
| PVN | 61.5 ± 8.87 | 138.25 ± 33.69 | 88.00 ± 59.30 | 206.50 ± 74.77 |
| SON | 129 ± 6.36 | 122.25 ± 12.64 | 207.25 ± 17.67 | 169.50 ± 45.75 |
| VMPO | 0.00 | 4.00 ± 0.58 | 2.00 ± 1.22 | 2.25 ± 0.48 |
| RCH | 107.50 ± 20.23 | 73.00 ± 14.70 | 128.00 ± 40.19 | 69.75 ± 8.54 |
| ADPN | 0.00 | 3.25 ± 2.93 | 3.25 ± 2.29 | 2.00 ± 0.71 |
| PeVN | 0.00 | 11.50 ± 4.33 | 56.5 ± 31.47 | 14.5 ± 3.28 |
| AN | 0.00 | 85.00 ± 10.87 | 92.00 ± 16.91 | 95.00 ± 12.51 |
| SCH | 0.00 | 368.67 ± 24.50 | 322.67 ± 27.57 | 175.25 ± 27.68 |
| MeA | 0.00 | 0.00 | 2.75 ± 1.38 | 0.00 |
| OXT-AVP | E16.5 | PN0 | PN7 | Adult |
|---|---|---|---|---|
| BNST | 0.00 | 53.75 ± 8.09 | 157.50 ± 11.91 | 53.50 ± 49.58 |
| PVN | 130.75 ± 16.27 | 68.75 ± 31.07 | 388.00 ± 72.50 | 93.50 ± 24.13 |
| SON | 13.50 ± 2.72 | 51.50 ± 18.31 | 168.75 ± 40.24 | 78.75 ± 29.56 |
| VMPO | 0.00 | 8.00 ± 2.80 | 14.50 ± 3.07 | 21.00 ± 12.92 |
| RCH | 11.75 ± 1.25 | 63.75 ± 23.67 | 86.00 ± 32.54 | 50.00 ± 4.42 |
| ADPN | 0.00 | 23.50 ± 6.96 | 58.75 ± 23.57 | 17.00 ± 14.02 |
| PeVN | 0.00 | 10.25 ± 4.25 | 91.00 ± 14.87 | 57.00 ± 37.41 |
| AN | 0.00 | 24.50 ± 14.15 | 148.25 ± 11.52 | 15.50 ± 4.17 |
| SCH | 0.00 | 0.67 ± 0.58 | 2.33 ± 0.29 | 3.00 ± 1.47 |
| MeA | 0.00 | 0.50 ± 0.50 | 7.50 ± 1.19 | 3.00 ± 1.78 |
Quantification of total number of each neuron population for different developmental stages (E16.5, PN0, PN7, and adult brain).
Results are expressed as mean ± S.E.M. (n = 4 brains).
BNST bed nucleus of stria terminalis, PVN paraventricular nucleus, SON supraoptic nucleus, VMPO ventromedial preoptic nucleus, RCH retrochiasmatic area, ADPN anterodorsal preoptic nucleus, PeVN periventricular nucleus, AN accessory nucleus, SCH suprachiasmatic nucleus, MeA medial amygdalar nucleus.