CDRH3 characteristics of IgM–BCRs using the IGHV5-6-1, IGHV5-9-3, and IGHV5-12-2 segments. A, CDRH3 length distribution of pooled IGH gene sequences of identified IGHV families of the ACR+ B cells. B, CDRH3 consensus logos of the mode CDRH3 length for pooled IGHV5-6-1, IGHV5-9-3, and IGHV5-12-2 IGH gene sequences. ACR+, acrolein-binding; BCR, B cell receptor; CDRH3, heavy-chain complementarity-determining region 3; IGH, immunoglobulin heavy chain; IgM, immunoglobulin M.