Table 1.
Deduced amino acid sequences of CDR3 of IgM–BCRs using the IGHV5-6-1, IGHV5-9-3, and IGHV5-12-2 segments
| IGHV | IGHD | IGHJ | IGHC | CDR3 AA sequence | Number of reads |
|---|---|---|---|---|---|
| IGHV5-6-1 | X | IGHJ3 | IGHM | CARLTGAYW | 884 |
| IGHV5-6-1 | IGHD1-1 | IGHJ2 | IGHM | CARHYYGSSYYFDYW | 379 |
| IGHV5-9-3 | IGHD1-1 | IGHJ2 | IGHM | CARHYYGSSYYFDYW | 378 |
| IGHV5-12-2 | IGHD1-1 | IGHJ2 | IGHM | CARHYYGSSYYFDYW | 276 |
| IGHV5-6-1 | IGHD1-1 | IGHJ3 | IGHM | CARHYYGSSYAYW | 223 |
| IGHV5-12-2 | IGHD2-9, 2-4 | IGHJ4 | IGHM | CARSTMITTMDYW | 217 |
| IGHV5-12-2 | X | IGHJ4 | IGHM | CARHGNYAMDYW | 191 |
| IGHV5-6-1 | IGHD2-3 | IGHJ2 | IGHM | CARHDGYFDYW | 149 |
| IGHV5-12-2 | IGHD2-3 | IGHJ2 | IGHM | CARHDGYYYFDYW | 121 |
| IGHV5-12-2 | IGHD2-8, 2-11, 2-10 | IGHJ1 | IGHM | CARHGNYWYFDVW | 95 |
| IGHV5-9-3 | IGHD1-1 | IGHJ4 | IGHM | CARHTTVVAMDYW | 91 |
| IGHV5-12-2 | IGHD1-1 | IGHJ1 | IGHM | CARHYYGSSYWYFDVW | 88 |
| IGHV5-6-1 | X | IGHJ2 | IGHM | CARHDYW | 86 |
| IGHV5-12-2 | IGHD1-1 | IGHJ2 | IGHM | CARHYYYGSSYYFDYW | 86 |
| IGHV5-12-2 | IGHD2-3 | IGHJ4 | IGHM | CARWLLRYYAMDYW | 85 |
| IGHV5-12-2 | IGHD2-8, 2-11, 2-10 | IGHJ4 | IGHM | CARHGNYAMDYW | 82 |
| IGHV5-6-1 | IGHD2-3 | IGHJ4 | IGHM | CARHYDGYYGAMDYW | 81 |
| IGHV5-12-2 | IGHD1-1 | IGHJ2 | IGHM | CARHYGSSYYFDYW | 79 |
| IGHV5-12-2 | IGHD1-1 | IGHJ1 | IGHM | CARHYYGSSWYFDVW | 76 |
| IGHV5-12-2 | X | IGHJ2 | IGHM | CARHWYFDYW | 58 |
| IGHV5-12-2 | IGHD1-1 | IGHJ2 | IGHM | CARHYYGSSYFDYW | 56 |
| IGHV5-6-1 | IGHD2-9, 2-4 | IGHJ2 | IGHM | CARHDYDYW | 52 |
| IGHV5-6-1 | IGHD2-11, 2-10 | IGHJ2 | IGHM | CARHSMVTTYYFDYW | 50 |
BCRs, B cell receptors; IGHC, immunoglobulin heavy chain constant region; IGHD, immunoglobulin heavy-chain diversity; IGHJ, immunoglobulin heavy-chain joining; IGHM, immunoglobulin heavy constant mu; IGHV, immunoglobulin heavy-chain variable; IgM, immunoglobulin M.