TABLE 2.
Mean Cr/NAA values, and for patients % fraction of abnormality
Controls | Patients | ||||
---|---|---|---|---|---|
Parcel | L/R | Young (n= 10) | Old (n= 10) | Good O/C | Poor O/C |
Total | 0.58±0.02 | 0.63±0.03 | 0.63±0.06 | 0.66±0.08 | |
1.01±0.06 | 1.00±0.06 | ||||
0.07±0.07% | 0.14±0.11% | 1.38±4.75% | 3.07±6.56% | ||
Ant Quad | L | 0.56±0.02 | 0.61±0.04 | 0.61±0.06 | 0.64±0.08 |
1.28±0.38 | 1.04±0.09 | ||||
0.38±0.66% | 1.09±2.58% | ||||
R | 0.06±0.23% | 0.08±0.18% | 0.62±0.07 | 0.67±0.10 | |
0.99±0.04 | 1.02±0.07 | ||||
0.85±1.93% | 2.91±4.24% | ||||
Post Quad | L | 0.58±0.03 | 0.62±0.04 | 0.60±0.05 | 0.65±0.07 |
0.99±0.01 | 1.03±0.09 | ||||
0.08±0.23% | 1.84±4.45% | ||||
R | 0.05±0.07% | 0.04±0.14% | 0.62±0.06 | 0.69±0.12 | |
1.16±0.32 | 1.05±0.04 | ||||
0.37±1.11% | 3.78±7.03% | ||||
Temporal | L | 0.61±0.03 | 0.65±0.05 | 0.66±0.08 | 0.69±0.10 |
1.18±0.08 | 1.06±0.09 | ||||
2.58±7.18% | 1.11±2.82% | ||||
R | 0.00% | 0.08±0.23% | 0.70±0.10 | 0.74±0.11 | |
1.18±0.15 | 1.09±0.07 | ||||
3.51±9.99% | 5.80±10.24% | ||||
Limbic | L | 0.64±0.04 | 0.70±0.06 | 0.69±0.07 | 0.72±0.10 |
1.11±0.12 | 1.12±0.10 | ||||
1.37±2.25% | 2.59±4.38% | ||||
R | 0.04±0.16% | 0.73±1.02% | 0.70±0.11 | 0.75±0.10 | |
1.09±0.10 | 1.19±0.17 | ||||
1.87±4.84% | 5.34±10.58% |
In the control columns, all parcels (combined left, right) from the young group are significantly different from the old group, all below p < 0.005. The fraction of limbic voxels that are abnormal is significantly larger in the old versus young group, 0.73 ± 1.02 versus 0.04 ± 0.16, p < 0.02. In the controls, each field has two entries (mean ± standard deviation): top, mean Cr/NAA over entire parcel; bottom, percentage of voxels that are scored as abnormal. In the patient columns, each field has three entries (mean and standard deviation): top, mean Cr/NAA over entire parcel; middle, mean Cr/NAA over the abnormal voxels only; bottom, percentage of abnormal voxels. The patient data are separated according to outcome: good, ILAE I, II; poor, ILAE III-VI.