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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: NMR Biomed. 2021 Mar 10;34(6):e4492. doi: 10.1002/nbm.4492

TABLE 2.

Mean Cr/NAA values, and for patients % fraction of abnormality

Controls Patients
Parcel L/R Young (n= 10) Old (n= 10) Good O/C Poor O/C
Total 0.58±0.02 0.63±0.03 0.63±0.06 0.66±0.08
1.01±0.06 1.00±0.06
0.07±0.07% 0.14±0.11% 1.38±4.75% 3.07±6.56%
Ant Quad L 0.56±0.02 0.61±0.04 0.61±0.06 0.64±0.08
1.28±0.38 1.04±0.09
0.38±0.66% 1.09±2.58%
R 0.06±0.23% 0.08±0.18% 0.62±0.07 0.67±0.10
0.99±0.04 1.02±0.07
0.85±1.93% 2.91±4.24%
Post Quad L 0.58±0.03 0.62±0.04 0.60±0.05 0.65±0.07
0.99±0.01 1.03±0.09
0.08±0.23% 1.84±4.45%
R 0.05±0.07% 0.04±0.14% 0.62±0.06 0.69±0.12
1.16±0.32 1.05±0.04
0.37±1.11% 3.78±7.03%
Temporal L 0.61±0.03 0.65±0.05 0.66±0.08 0.69±0.10
1.18±0.08 1.06±0.09
2.58±7.18% 1.11±2.82%
R 0.00% 0.08±0.23% 0.70±0.10 0.74±0.11
1.18±0.15 1.09±0.07
3.51±9.99% 5.80±10.24%
Limbic L 0.64±0.04 0.70±0.06 0.69±0.07 0.72±0.10
1.11±0.12 1.12±0.10
1.37±2.25% 2.59±4.38%
R 0.04±0.16% 0.73±1.02% 0.70±0.11 0.75±0.10
1.09±0.10 1.19±0.17
1.87±4.84% 5.34±10.58%

In the control columns, all parcels (combined left, right) from the young group are significantly different from the old group, all below p < 0.005. The fraction of limbic voxels that are abnormal is significantly larger in the old versus young group, 0.73 ± 1.02 versus 0.04 ± 0.16, p < 0.02. In the controls, each field has two entries (mean ± standard deviation): top, mean Cr/NAA over entire parcel; bottom, percentage of voxels that are scored as abnormal. In the patient columns, each field has three entries (mean and standard deviation): top, mean Cr/NAA over entire parcel; middle, mean Cr/NAA over the abnormal voxels only; bottom, percentage of abnormal voxels. The patient data are separated according to outcome: good, ILAE I, II; poor, ILAE III-VI.