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Smpd1 gene knockout prevented proteinuria and glomerular sclerosis during hHcy. A. Urinary protein excretion of different groups of mice (n=8–13). B. Representative images and summarized data showing the glomerular morphological changes (periodic acid-Schiff staining) of different groups of mice (n=6). * P<0.05 vs. ND group. # P<0.05 vs. WT/WT group.
