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. 2021 Mar 25;7(1):85–92. doi: 10.5114/ceh.2021.104472

Table 4.

Comparison between the different parameters in group B before and after 6 months of treatment (n = 40)

Before treatment After 6 months of treatment Test of sig. p
AST (IU/ml)
Min.-Max. 69-150 10-25 t = 23.02* < 0.001*
Mean ±SD 95 ±21 15.6 ±4
ALT (IU/ml)
Min.-Max. 88-220 11-30 t = 19.797* < 0.001*
Mean ±SD 135.5 ±37.9 19.5 ±6.4
HBV DNA (IU/ml)
Negative 0 (0%) 35 (87.5%) χ2 = 62.222* McNp < 0.001*
Positive 40 (100%) 5 (12.5%)
FIB-4
Min.-Max. 0.4-1.8 0.2-1.0 Z = 5.512* < 0.001*
Median (IQR) 0.8 (0.6-1.1) 0.3 (0.3-0.4)
APRI
Min.-Max. 0.5-1.0 0.1-0.3 Z = 5.512* < 0.001*
Median (IQR) 0.6 (0.6-0.8) 0.1 (0.1-0.1)

χ2 – chi square test, McN – McNemar test, t – paired t-test, Z – Wilcoxon signed ranks test, p – p value for comparing between the studied periods, *statistically significant at p ≤ 0.05