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. 2021 May 15;21:199. doi: 10.1186/s12883-021-02230-8

Table 1.

Summary of the characteristics of Bickerstaff’s brainstem encephalitis-related cases reported in the literature

Publisher Publication time Country Infection types Gender Age GQ1bIgG
antibody
CSFa test Imaging examination
Kikuchi,M et al. [10] 1997 Japan Mycoplasma pneumoniae male 7 positive Protein cell dissociation T2 high signal around aqueduct
Steer AC.et al. [11] 2006 Japan Mycoplasma pneumoniae male 11 positive Protein and cell normal MRI showed diffuse meningeal enhancement and patchy hyperintensity in the spinal cord
Hussain AM [13] 2007 UK Campylobacter jejuni male 54 negative Protein and cell normal T2 hyperintense area in the brainstem
Masahiro Mori et al. [14] 2008 Japan Campylobacter jejuni female 26 positive Protein cell dissociation Not done
Kanzaki A et al. [15] 1995 Japan Cytomegalovirus female 17 positive Protein and cell normal Brain CT and MRI were normal
Tagawa Y,et a [7] 2000 Japan Varicella zoster virus male 59 positive Protein cell dissociation No abnormality was found
Rho, YI [8] 2014 Korea Epstein Barr virus male 2 negative Protein and cell normal MRI was normal
Wali GM.et al. [16] 1991 India Salmonella typhi male 14 Not recorded Protein and cell normal Brain CT was normal

Bun Sheng

et al. [17]

2010 Hong Kong, China Salmonella Paratyphi A female 28 positive Protein and cell normal brainstem edema with patchy T2 hyperintensity
Gianni Coriolani et al. [12] 2020 Italy Mycoplasma pneumoniae Not recorded 7.5 Not recorded Protein and cell normal 8 mm × 4 mm in T2-FLAIR sequences in the left thalamic area and the posterior left medulla oblongata-spinal

aCSF Cerebrospinal fluid