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. 2021 Apr 21;22(9):4345. doi: 10.3390/ijms22094345

Scheme 1.

Scheme 1

Representation of the VvROMT sequential di-methylation reaction. VvROMT catalyzes the sequential di-methylation at the 3/5-OH position on resveratrol to yield pterostilbene, mediated by the transfer of two methyl group from the co-substrate S-adenosylmethionine (SAM).