Table 3.
Simulation results of the number of detectable metastases for two different metastatic formation constants. For the median size of detectable metastases, the 95% confidence interval is presented in parentheses.
| Number of Detectable Metastases | Metastatic Formation Constant (%/day/g) | Formation Time (d) | Median Size of Detectable Metastases | Total Number of Metastases | Total Metastatic Burden (cm3) |
|---|---|---|---|---|---|
| 1 | 0.16 | 1390 | 0.80 (0.19–9.0) | 7.70 | 1.80 |
| 5 | 0.16 | 1750 | 2.0 (0.20–23.8) | 18.7 | 23.8 |
| 10 | 0.16 | 1990 | 3.5 (0.21–35.1) | 33.6 | 80.2 |
| 20 | 0.16 | 2290 | 5.0 (0.21–46.7) | 67.1 | 228 |
| 1 | 2.56 | 1070 | 0.40 (0.18–3.0) | 47.3 | 0.94 |
| 5 | 2.56 | 1220 | 0.54 (0.19–5.0) | 91.3 | 5.72 |
| 10 | 2.56 | 1310 | 0.66 (0.19–7.2) | 136 | 14.7 |
| 20 | 2.56 | 1410 | 0.81 (0.19–9.7) | 220 | 37.7 |