Table 1.
The aqueous solubilities (g/100 mL) at room temperature, acid/base chemistry, molecular weight, and percent magnesium composition of common magnesium supplements.
| Form (Oxide/Salt/Chelate) |
Acid/Base Chemistry | Solubility (g/100 mLs H2O) |
MW g/mol (%Mg) | Reference |
|---|---|---|---|---|
| Magnesium Oxide | Alkaline | 0.010 | 40.30 (60.3) | [25] |
| Magnesium Citrate | Acidic (pKa1 = 3.13) | 20 | 214.41 (11.3) | [26] |
| Magnesium Chloride | Neutral | 54.0 | 95.21 (25.5) | [27] |
| Magnesium Sulfate | Acidic (pKa1 = 3.0; pKa2 = 1.99) | 35.7 | 120.37 (20.1) | [25] |
| Magnesium Orotate | Acidic (pKa1 = 2.83) | Slightly Soluble | 334.48 (7.2) | [28] |
| Magnesium Taurate | Acidic (pKa = 1.50) | Slightly Soluble | 272.57 (8.9) | [29] |
| Magnesium Aspartate | Acidic (pKa1 = 1.88; pKa3 = 3.65) | 4.0 | 288.49 (8.5) | [30] |
| Magnesium Threonate | Acidic (pKa1 = 3.4) | Soluble | 294.50 (8.3) | [31] |
| Magnesium Malate | Acidic (pKa1 = 3.46; pKa2 = 5.10) | Slightly Soluble | 156.37 (15.5) | [32,33] |
| Magnesium Bisglycinate | Acidic (pKa = 2.34) | 1.36 | 172.42 (14.1) | In-house |
| Magnesium Hydroxide | Alkaline | 0.00069 | 58.32 (41.7) | [25] |
| Magnesium Carbonate | Weakly Alkaline | 0.18 | 84.31 (28.8) | [26] |
| Magnesium Triglycine | Acidic | 169 | 265.50 (9.1) | This Work |