Table 5.
Odds ratio of region-specific cardiovascular fat tissue and noninvasive visceral adipose indices with risk of subclinical hypothyroidism according to absolute risk of cardiovascular event in 10 years by Framingham risk score
| Variables | PCFa | TATa | ABSI | BRI | CVAI | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
| Low risk | |||||||||||||||
| Men | |||||||||||||||
| Model 1 | 0.56 | (0.21-1.50) | .25 | 1.32 | (0.56-3.10) | .53 | 1.31 | (0.56-3.07) | .54 | 0.79 | (0.29-2.14) | .65 | 0.96 | (0.26-3.14) | .93 |
| Model 2 | 0.52 | (0.19-1.41) | .20 | 1.24 | (0.52-2.95) | .62 | 1.24 | (0.52-2.94) | .62 | 0.80 | (0.30-2.18) | .67 | 0.96 | (0.38-2.45) | .93 |
| Model 3 | 0.48 | (0.17-1.32) | .15 | 1.24 | (0.51-3.05) | .63 | 1.18 | (0.49-2.82) | .71 | 0.80 | (0.28-2.27) | .67 | 0.96 | (0.35-2.66) | .94 |
| Women | |||||||||||||||
| Model 1 | 0.84 | (0.31–2.23) | .72 | 3.00 | (0.78-11.55) | .11 | 0.69 | (0.29-1.61) | .39 | 2.03 | (1.00-4.13) | .049 | 0.91 | (0.28-2.44) | .88 |
| Model 2 | 0.64 | (0.23–1.78) | .40 | 2.60 | (0.67-10.15) | .17 | 0.61 | (0.26-1.44) | .26 | 1.82 | (0.89-3.73) | .10 | 0.71 | (0.20-2.52) | .60 |
| Model 3 | 0.64 | (0.23–1.77) | .39 | 2.83 | (0.71-11.34) | .14 | 0.60 | (0.25-1.43) | .25 | 1.86 | (0.87-3.96) | .11 | 0.87 | (0.23-3.25) | .83 |
| Men | |||||||||||||||
| Model 1 | 0.98 | (0.54-1.79) | .96 | 1.02 | (0.55-1.90) | .95 | 1.54 | (0.84-2.81) | .16 | 0.93 | (0.51-1.69) | .82 | 0.81 | (0.45-1.48) | .50 |
| Model 2 | 0.94 | (0.51-1.72) | .84 | 0.94 | (0.50-1.78) | .85 | 1.42 | (0.76-2.65) | .28 | 0.92 | (0.50-1.67) | .78 | 0.81 | (0.44-1.47) | .48 |
| Model 3 | 1.00 | (0.53-1.90) | .99 | 1.04 | (0.53-2.05) | .91 | 1.47 | (0.78-2.77) | .23 | 1.03 | (0.54-1.97) | .92 | 0.90 | (0.46-1.77) | .76 |
| Women | |||||||||||||||
| Model 1 | 2.92 | (0.70-12.09) | .14 | 3.17 | (1.02-5.22) | .03 | 1.19 | (0.32-4.43) | .80 | 6.85 | (1.08-10.61) | .02 | 6.85 | (1.03-11.61) | .03 |
| Model 2 | 2.69 | (0.62-11.63) | .19 | 3.26 | (1.07-5.54) | .03 | 1.16 | (0.31-4.40) | .82 | 6.91 | (1.03-10.23) | .03 | (1.01-12.57) | .04 | |
| Model 3 | 4.05 | (0.73-22.42) | .11 | 4.01 | (1.01-6.64) | .04 | 1.39 | (0.34-5.74) | .65 | 7.04 | (1.02-11.29) | .03 | 7.81 | (1.01-12.03) | .04 |
Model 1: Unadjusted.
Model 2: Adjusted for age and smoking.
Model 3: Adjusted for factors in model 2 plus SBP, FBG, LDL-C, and HDL-C.
Abbreviations: ABSI, a body shape index; BMI, body mass index; BRI, body roundness index; CVAI, Chinese visceral adiposity index; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; OR, odds ratio; PCF, pericardial fat; SBP, systolic blood pressure; TAT, thoracic periaortic adipose tissue.
a Model 2: Adjusted for age, smoking, and BMI.