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. 2021 Feb 5;5(5):846–864. doi: 10.1002/hep4.1679

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© 2021 The Authors. Hepatology Communications published by Wiley Periodicals LLC on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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FIG. 7 — LDNP treatment decreased circulating endotoxin level through Nrf2 activation. (A) Western blot for nuclear Nrf2 protein in ileum tissues of LDNPs‐treated mice fed with alcohol. Histone H3 serves as a loading control. (B,C) Relative mRNA level of Nrf2 and Nqo1 in mouse ileum. (D) Dihydroethidium staining for the measurement of ROS in the ileum tissues. (E) Western blots for tight junction proteins in the ileum tissue. (F) Serum endotoxin levels. Data are expressed as the mean ± SEM (n = 5‐7 mice/group). *P < 0.05.