Figure 1.

Schematic illustration of the structure of an amyloid fibril. Amyloid fibrils typically show needle-like and unbranched morphology, which consists of several protofilaments a few nanometers in width and around a micrometer in length that are laterally bundled. Each protofilament shows a cross-β structure, where β-strands are stacked perpendicular to the long axis of the fibril.